Reversible covalent assemblies are constitutionally dynamic, having the ability to modify their constitution by incorporating or exchanging  their components. Thus, after macromolecular dissociation, reconstruction in the presence of a competing equilibrium results in exchange of polymer building blocks to yield an entirely new material. The ability to reshuffle constituents through assembly-disassembly is being employed to induce dramatic topological rearrangements in solution. This research exploits reversible covalent chemistries to prepare adaptive materials and to increase understanding of telechelic polymer self-assembly into dynamic covalent macromolecular systems.